United States (multi-state surveillance)
Sin Nombre hantavirus HPS · Western and southwestern US · preliminary historical
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Summary
Annual sporadic Sin Nombre virus (SNV) HPS reporting through the CDC National Notifiable Diseases Surveillance System (NNDSS) for 2024. Cases were distributed across the western US — particularly Arizona (which recorded an anomalous spike to 11 confirmed cases versus a recent baseline of 1–3 per year), Colorado, New Mexico, California, Washington, Louisiana, and Montana. The principal reservoir is the deer mouse (Peromyscus maniculatus); most cases are exposure-driven (rodent-contaminated cabins, sheds, and outbuildings). CDC's cumulative surveillance reported 890 hantavirus disease cases in the United States from 1993 through the end of 2023, with overall case-fatality of approximately 35%. Finalized 2024 national totals were not extractable from open-access CDC pages at access time, so case counts here are intentionally left at zero rather than estimated.
Why this matters
The 2024 Arizona spike (11 confirmed cases vs. 1–3 baseline) was a notable signal that drew journalistic and academic attention. Otherwise the annual SNV burden in the US has remained low but persistent since 1993, with case-fatality of about one-third — among the highest of any acute respiratory disease tracked by CDC.
Sources
- T1 Reported Cases of Hantavirus Disease Centers for Disease Control and Prevention · 2026-05-07
- T1 Hantavirus Case Definition and Reporting Centers for Disease Control and Prevention · 2026-05-07